Second, there could also be an age-associated resistance to a decrease dose of lysine ingestion with respect to glucose metabolism as within the case for muscle protein synthesis response.

The exception to the rule is the DOT1 household, members of which methylate K79 in the globular area of histone H3 and that are structurally not associated to SET-area proteins four - 6 Current work means that SET-domain-containing proteins methylate a number of proteins in addition to histones (see later)